Solid Phase Peptide Synthesis by Four Component Condensation: Peptide Formation on an Isocyano Polymer Support
Open Access
- 1 September 1981
- journal article
- research article
- Published by Walter de Gruyter GmbH in Zeitschrift für Naturforschung B
- Vol. 36 (9) , 1202-1203
- https://doi.org/10.1515/znb-1981-0933
Abstract
Coupling of various protected amino acids or small peptides on an isocyano polymer and in the presence of 1-methyl-3-formylindole demonstrates the feasibility of peptide formation by 4 component condensation on a polymer support and the final peptide is detached from the resin by 50% trifluoroacetic acid in acetonitrile at room temperature.This publication has 1 reference indexed in Scilit:
- Peptide synthesis using the four-component condensation (Ugi reaction)Journal of the American Chemical Society, 1977