Dissolution of Uric Acid Calculi with Systemic Alkalization

Abstract
Patients (14) with uric acid calculi in the renal pelvis and calices (10) or ureter (4) with constant i.v. infusion of a one-sixth molar lactate solution were treated. Dissolution was successful in all but 2 cases. The success of therapy is believed to be related to the sustained urinary alkalization obtained with intavenous infusion compared to the intermittent alkalization that occurs when oral agents are used.