Effects of Androsterone on Atherogenesis and Plasma Lipids in Cockerels

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Abstract
The effects of androsterone and testosterone propionate on atheroma and plasma lipids shifts induced by cholesterol feeding in cockerels were compared. Both compounds produced significant inhibition of coronary arterial atheroma. Aortic atherogenesis was not affected. The effects on plasma lipids were similar; non-significant reduction in cholesterol (C), significant decrease in phospholipid (P) with elevated C/P ratios. Testosterone propionate, but not androsterone, caused a significant reduction in testicular weight; both compounds stimulated comb growth.

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