The levels of superoxide dismutase, catalase, and carbonic anhydrase in erythrocytes of patients with Down's syndrome

Abstract
The levels of cytoplasmic superoxide dismutase (SOD1), catalase (CAT'ase), and carbonic anhydrase isoenzymes (CA-B and CA-C) were determined in the erythrocytes from 11 male patients with Down's syndrome. The levels of SOD1 and CAT'ase, as well as CA-B showed significant increases compared with those in normal controls, whereas the CA-C level did not change substantially. In addition, a positive correlation was noted between the levels of SOD1 and of CAT'ase (r=0.764).