Hyperinsulinemia in Cord Blood in Mothers With Type 2 Diabetes and Gestational Diabetes Mellitus in New Zealand
Open Access
- 1 June 2006
- journal article
- research article
- Published by American Diabetes Association in Diabetes Care
- Vol. 29 (6) , 1345-1350
- https://doi.org/10.2337/dc05-1677
Abstract
OBJECTIVE—In genetically diabetes-prone populations, maternal diabetes during pregnancy increases the risk of their children developing diabetes and obesity (the vicious cycle of type 2 diabetes). Fetal hyperinsulinemia at birth acts as a marker of this risk. We therefore examined whether cord insulin and leptin concentrations are increased in offspring of Maori and Pacific Island mothers with type 2 and gestational diabetes mellitus (GDM) and varying degrees of glycemic control (HbA1c).Keywords
This publication has 28 references indexed in Scilit:
- Effect of Treatment of Gestational Diabetes Mellitus on Pregnancy OutcomesNew England Journal of Medicine, 2005
- Term birthweight centiles for babies from New Zealand's main ethnic groupsAustralian and New Zealand Journal of Obstetrics and Gynaecology, 2004
- Diagnosis and Classification of Diabetes MellitusDiabetes Care, 2004
- Intrauterine Hyperglycemia Is Associated With an Earlier Diagnosis of Diabetes in HNF-1α Gene Mutation CarriersDiabetes Care, 2002
- Determinants of the Development of Diabetes (Maturity-Onset Diabetes of the Young-3) in Carriers of HNF-1α MutationsDiabetes Care, 2002
- Insulin Degradation: Progress and PotentialEndocrine Reviews, 1998
- Overweight and obesity in infants of mothers with long-term insulin-dependent diabetes or gestational diabetesInternational Journal of Obesity, 1997
- Fetal Hyperinsulinism in Offspring of Diabetic MothersAnnals of the New York Academy of Sciences, 1993
- Excessive Obesity in Offspring of Pima Indian Women with Diabetes during PregnancyNew England Journal of Medicine, 1983
- Banting Lecture 1980. Of pregnancy and progenyDiabetes, 1980