Enantioselective total synthesis of the phytotoxic lactone herbarumin I

21 March 2001

journal article
research article
Published by Royal Society of Chemistry (RSC) in Chemical Communications

No. 7,p. 671-672
https://doi.org/10.1039/b101148k

Abstract

A concise total synthesis of the potent herbicide herbarumin I (1) is presented based on an (E)-selective RCM reaction forging the 10-membered ring of this macrolide.

Keywords

ENANTIOSELECTIVE
TOTAL SYNTHESIS
HERBICIDE
FORGING
LACTONE
MEMBERED
RCM
CONCISE
PHYTOTOXIC
MACROLIDE