Polymer membrane sensors for continuous intravascular monitoring of blood pH
- 1 April 1976
- journal article
- research article
- Published by American Physiological Society in Journal of Applied Physiology
- Vol. 40 (4) , 644-647
- https://doi.org/10.1152/jappl.1976.40.4.644
Abstract
A new type of pH sensor suitable for chronic intra-vascular implantation by virtue of its small size, flexibility, and ruggedness was constructed and evaluated. The pH-sensitive element was a thin film of an elastromeric polymer made ion permselective to proteons by adding a lipophilic, specific H+-ion carrier. This was coated onto small diameter silver wires to form sensors. In preliminary trials in anesthetized dogs, the sensors permitted continuous, accurate in vivo blood pH measurement with rapid response (less than 0.1 s).This publication has 3 references indexed in Scilit:
- Protonic conductance across phospholipid bilayer membranes induced by uncoupling agents for oxidative phosphorylation.Proceedings of the National Academy of Sciences, 1968
- Continuous measurement of blood pH with an indwelling arterial glass electrode.Journal of Applied Physiology, 1967
- A new class of uncoupling agents — Carbonyl cyanide phenylhydrazonesBiochemical and Biophysical Research Communications, 1962