Effect of Vitamins A and D on Resistance to Infection

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Abstract
Young white rats were inoculated by intraperitoneal injection of a standard suspension of organisms after 4, 6, 8 and 10 weeks on a vitamin A-free diet. Markedly decreased resistance to such infection, compared with controls receiving cod liver oil, was demonstrated before other signs of vitamin A deficiency appeared. No such suscpetibility to similar inoculations was found in young rats on a diet deficient in vitamin D, compared to controls protected by irradiated ergosterol.