Specific Monoclonal Antibody Raised Against the p33ING1 Tumor Suppressor
- 1 December 1997
- journal article
- Published by Mary Ann Liebert Inc in Hybridoma
- Vol. 16 (6) , 537-540
- https://doi.org/10.1089/hyb.1997.16.537
Abstract
An IgG1 mouse monoclonal antibody (CAb1) was produced against human recombinant p33ING1. The antibody is able to recognize native and denatured antigen in ELISA and Western blot protocols, respectively. CAb1 can be used to specifically detect the p33ING1 protein in dot blot and Western immunoblot protocols of both human and mouse cell lysates. In addition, this antibody is also useful for cellular localization of native and ectopically overexpressed p33ING1 protein by indirect immunofluorescence.Keywords
This publication has 7 references indexed in Scilit:
- Extension of the Replicative Life Span of Human Diploid Fibroblasts by Inhibition of the p33ING1 Candidate Tumor SuppressorMolecular and Cellular Biology, 1997
- Cellular localization and chromosome mapping of a novel candidate tumor suppressor gene (ING1)Cytogenetic and Genome Research, 1997
- Suppression of the novel growth inhibitor p33ING1 promotes neoplastic transformationNature Genetics, 1996
- THE TUMOR SUPPRESSOR GENESAnnual Review of Biochemistry, 1993
- Tumor Suppressor GenesScience, 1991
- The catalytic subunit of cAMP-dependent protein kinase induces expression of genes containing cAMP-responsive enhancer elementsNature, 1988
- A better cell line for making hybridomas secreting specific antibodiesNature, 1978