Regrowth of Grafted Human Scalp Hair after Removal of the Bulb

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Abstract
The bulbar region of the hair follicle contains the dermal papilla, hair germinative epithelial component, and active melanocytes. Thus, it has been assumed that the bulbar region plays a central role in hair growth, differentiation, and pigmentation. To assess the regenerative capacity of human hair. Individual anagen hair follicles were isolated from the occipital scalp and grafted onto the leg after removal of the bulb. The grafts of follicles from which the bulb and complete papilla have been excised regenerated new papillae and grew new pigmented hairs. The middle portion of the outer root sheath and dermal sheath may also contain epithelial, mesenchymal, and melanocyte reservoirs.