Seasonal Variation in the Incidence of Deep Vein Thrombosis in Patients With Deficiency of Protein C or Protein S
Open Access
- 1 July 2002
- journal article
- research article
- Published by SAGE Publications in Clinical and Applied Thrombosis/hemostasis
- Vol. 8 (3) , 231-237
- https://doi.org/10.1177/107602960200800306
Abstract
An attempt was made to identify circaseptanal or seasonal variation of deep vein thrombosis (DVT) in a population with protein C or protein S deficit. Forty-four patients with DVT and protein C or protein S deficit were studied for 1 year. A significant circannual rhythm was found for the total population that peaked during winter. There was also a significant falling circaseptanal rhythm on Fridays. These observations may optimize an adequate and precise anticoagulant therapy in patients witi protein C or protein S deficits.Keywords
This publication has 14 references indexed in Scilit:
- Circadian Variation in the Occurrence of Fatal Pulmonary Embolism. Differences Depending on Sex and Age.Japanese Heart Journal, 1994
- A novel dysfunctional protein C (Protein C Padua 2) associated with a thrombotic tendency: substitution of Cys for Arg‐1 results in a strongly reduced affinity for binding of Ca++British Journal of Haematology, 1993
- Sudden Death May Show a Circadian Time of Risk Depending on Its Anatomo-clinical Causes and Age.Japanese Heart Journal, 1993
- Circadian Variations in Myocardial IschemiaPublished by American Medical Association (AMA) ,1991
- Seasonal periodicity in fatal pulmonary thromboembolismThe Lancet, 1990
- Circadian Variation in the Frequency of Onset of Acute Myocardial InfarctionNew England Journal of Medicine, 1985
- Increases in platelet and red cell counts, blood viscosity, and arterial pressure during mild surface cooling: factors in mortality from coronary and cerebral thrombosis in winter.BMJ, 1984
- Current status of pulmonary thromboembolic disease: Pathophysiology, diagnosis, prevention, and treatmentAmerican Heart Journal, 1982
- Circadian rhythm of human blood viscosity12Biorheology, 1973
- A ‘New’ Congenital Haemorrhagic Condition due to the Presence of an Abnormal Factor X (Factor X Friuli): Study of a Large KindredBritish Journal of Haematology, 1970