Insertional mutagenesis strategies in zebrafish
Open Access
- 1 January 2007
- journal article
- review article
- Published by Springer Nature in Genome Biology
- Vol. 8 (Suppl 1) , S9
- https://doi.org/10.1186/gb-2007-8-s1-s9
Abstract
We review here some recent developments in the field of insertional mutagenesis in zebrafish. We highlight the advantages and limitations of the rich body of retroviral methodologies, and we focus on the mechanisms and concepts of new transposon-based mutagenesis approaches under development, including prospects for conditional 'gene trapping' and 'gene breaking' approaches.Keywords
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