Abstract
Since it had been shown that cholesterol is broken down in the bodies of herbivorous animals, comparison was made of the rate of degradation of herbivora and carnivora when fed cholesterol rich diets. The cat does not appear to be able to destroy cholesterol at a much greater rate than the rabbit. However, the distribution of the cholesterol fed is markedly different in the two species. Deposition of cholesterol was many times greater in the liver of the cat than in that of the rabbit. In the rabbit cholesterol was deposited generally throughout the body while in the cat concentration occurred in the liver. The ease with which atherosclerosis is produced in rabbits may be connected with the inability of the animal to regulate properly the distribution of sterol. In neither animal does deposition of fed cholesterol occur in the brain.

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