A clickable inhibitor reveals context-dependent autoactivation of p90 RSK
Open Access
- 28 January 2007
- journal article
- research article
- Published by Springer Nature in Nature Chemical Biology
- Vol. 3 (3) , 156-160
- https://doi.org/10.1038/nchembio859
Abstract
No abstract availableKeywords
This publication has 31 references indexed in Scilit:
- BI-D1870 is a specific inhibitor of the p90 RSK (ribosomal S6 kinase) isoformsin vitroandin vivoBiochemical Journal, 2006
- The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activityThe EMBO Journal, 2006
- Inhibiting p90 Ribosomal S6 Kinase Prevents Na + -H + Exchanger–Mediated Cardiac Ischemia-Reperfusion InjuryCirculation, 2006
- Role of p90 Ribosomal S6 Kinase–Mediated Prorenin-Converting Enzyme in Ischemic and Diabetic MyocardiumCirculation, 2006
- Ribosomal protein S6 phosphorylation is a determinant of cell size and glucose homeostasisGenes & Development, 2005
- Structural Bioinformatics-Based Design of Selective, Irreversible Kinase InhibitorsScience, 2005
- Upstream and downstream of mTORGenes & Development, 2004
- 90-kDa Ribosomal S6 Kinase Is Phosphorylated and Activated by 3-Phosphoinositide-dependent Protein Kinase-1Journal of Biological Chemistry, 1999
- Identification of Serine 380 as the Major Site of Autophosphorylation of Xenopus pp90rskBiochemical and Biophysical Research Communications, 1997
- Comparison of the specificities of p70 S6 kinase and MAPKAP kinase‐1 identifies a relatively specific substrate for p70 S6 kinase: the N‐terminal kinase domain of MAPKAP kinase‐1 is essential for peptide phosphorylationFEBS Letters, 1995