1,3-Diphenyl-1H-pyrazolo[3,4-b]quinoline: A Versatile Fluorophore for the Design of Brightly Emissive Molecular Sensors
- 1 December 2002
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 4 (26) , 4647-4650
- https://doi.org/10.1021/ol027025i
Abstract
[structure: see text] The 1,3-diphenyl-1H-pyrazolo[3,4-b]-quinoline chromophore is a versatile building block for the construction of brightly fluorescent molecular sensors. Facile synthetic procedures allow integration of the chromophore into fluorophore-spacer-receptor systems as well as fluoroionophores operating via intramolecular charge transfer. Whereas the former photoinduced electron-transfer probes show strong analyte-induced fluorescence enhancement, the latter exhibit bright ratiometric dual emission. Employing prototype macrocyclic receptors, the favorable signaling features for metal ion recognition are demonstrated.Keywords
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