Novel macrocyclic antibiotics: Megovalicins A, B, C, D, G and H. I. Screening of antibiotics-producing myxobacteria and production of megovalicins.
- 1 January 1988
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 41 (4) , 433-438
- https://doi.org/10.7164/antibiotics.41.433
Abstract
New antibiotics belonging to macrocyclic were discovered and named megovalicins A, B, C, D, G and H. The antibiotics were accumulated endogeneously by a newly isolated myxobacterium identified as Myxococcus flavescens. Tank culture of the bacterium for 4 days gave 8.8 g cells/liter on a wet basis, and 4.8, 7.1, 20.0, 0.4, 3.75 and 15.0 .mu.g of megovalicins A, B, C, D, G and H respectively were obtained from 1 g wet cells.This publication has 10 references indexed in Scilit:
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