Serologische Hepatitis-B-Marker bei Porphyria cutanea tarda

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Abstract
Using several seromarkers for hepatitis B virus the frequency of previous hepatitis B in patients with porphyria cutanea tarda (PCT) as a possible manifestation factor was determined. As chronic hepatitis is frequently associated with an increase of factor VIII-associated antigen, this was included in the investigation. Of 60 investigated patients, 28 (47%) had hepatitis. In 30% an increase of factor VIII-associated antigen was found. Hepatitis B virus infection as a manifestation factor may be of considerable importance in porphyria cutanea tarda when genetic disposition (uroporphyrinogen-decarboxylase deficiency) is present.
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