Sp1 and Sp3 Transcription Factors Mediate Interleukin-1β Down-regulation of Human Type II Collagen Gene Expression in Articular Chondrocytes
Open Access
- 1 October 2003
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 278 (41) , 39762-39772
- https://doi.org/10.1074/jbc.m303541200
Abstract
No abstract availableKeywords
This publication has 46 references indexed in Scilit:
- The TATA-containing core promoter of the type II collagen gene (COL2A1) is the target of interferon-gamma-mediated inhibition in human chondrocytes: requirement for Stat1alpha, Jak1 and Jak2Biochemical Journal, 2003
- SP3 Represses the SP1-mediated Transactivation of the HumanCOL2A1 Gene in Primary and De-differentiated ChondrocytesJournal of Biological Chemistry, 2001
- SOX9 directly regulates the type-ll collagen geneNature Genetics, 1997
- Identification of a Minimum Enhancer Sequence for the Type II Collagen Gene Reveals Several Core Sequence Motifs in Common with the Link Protein GenePublished by Elsevier ,1996
- Interleukin-1 beta-modulated gene expression in immortalized human chondrocytes.Journal of Clinical Investigation, 1994
- Effect of transforming growth factor-β1 (TGF-β1) on matrix synthesis by monolayer cultures of rabbit articular chondrocytes during the dedifferentiation processExperimental Cell Research, 1992
- Comparative Effects of Interleukin-1 and Tumor Necrosis Factor-α on Collagen Production and Corresponding Procollagen mRNA Levels in Human Dermal FibroblastsJournal of Investigative Dermatology, 1991
- Interleukin-1 -induced suppression of type II collagen gene transcription involves DNA regulatory elementsExperimental Cell Research, 1990
- Minireview Interleukin-1 and osteoarthritisLife Sciences, 1987
- Effect of a monocyte cell factor (MCF) on collagen production in cultured articular chondrocytes: Role of prostaglandin E2Biochemical and Biophysical Research Communications, 1984