Therapiemöglichkeiten bei nicht resektablen Lebermetastasen Percutane radiologische Interventionen
- 1 February 1999
- journal article
- research article
- Published by Springer Nature in Der Chirurg
- Vol. 70 (2) , 133-140
- https://doi.org/10.1007/s001040050620
Abstract
In patients with irresectable liver metastases the following spectrum of oncological concepts is in use. Percutaneous interventional methods allows for an optimized local control rate in strictly intrahepatic disease. Regional short-term time chemotherapy and transarterial chemoembolization (TACE) belong to regional methods. As local ablative methods, intratumoral drug application, endotumoral chemotherapy and alcohol instillation can be used. The most promising thermotherapeutic strategies are radiofrequency and laser-induced thermotherapy (LITT). In a prospective study 278 patients suffering from liver metastases were treated with MR-guided LITT and exact data for the local control rate and survival rate were evaluated. The overall cumulative survival rate (Kaplan-Meier) of patients with liver metastases was 40.8 months (median: 40.97 months, 95 % confidence interval 36.3–45.2).Keywords
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