DNA analysis in human disease.
- 1 December 1986
- journal article
- review article
- Published by BMJ in Journal of Clinical Pathology
- Vol. 39 (12) , 1281-1295
- https://doi.org/10.1136/jcp.39.12.1281
Abstract
The analysis of human DNA using recombinant DNA technology is fast becoming an integral part of the diagnosis, assessment, and prevention of inherited and somatic genetic disease. The rationale underlying these methods of analysis is discussed, and the nature and extent of mutational change in heritable disorders and neoplastic development is outlined.Keywords
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