Rise in Plasma Beta-Endorphin, ACTH, and Cortisol in Cancer Patients Undergoing Whole Body Hyperthermia
- 1 September 1987
- journal article
- research article
- Published by Georg Thieme Verlag KG in Hormone and Metabolic Research
- Vol. 19 (09) , 441-443
- https://doi.org/10.1055/s-2007-1011847
Abstract
It has been previously reported that sauna-induced fevers (∼ 39°C) result in rises of β-endorphins in normal volunteers. This report describes changes in plasma β-endorphins in cancer patients undergoing whole body hyperthermia (40.5°C to 41.8°C). Results presented show that there is a linear relationship between thermal stress, defined in terms of core temperature and/or duration of hyperthermia, and the quantitative rise in plasma β-endorphin levels. Data relating to changes in ACTH and cortisol levels are in a single temperature range (41.5°C-41.8°C) are also reported.Keywords
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