Purification of Human α1 Antiprotease-Pancreatic Elastase Complex. Interaction with Homologous Elastin
- 1 January 1984
- journal article
- research article
- Published by Taylor & Francis in Connective Tissue Research
- Vol. 12 (2) , 165-174
- https://doi.org/10.3109/03008208408992781
Abstract
A human .alpha.1-antiprotease (.alpha.1.AP)-human pancreatic elastase (HPE11) complex was isolated from plasma, or prepared from commercial .alpha.1.AP. The complex was identified and isolated by affinity chromatography, using concanavalin A or IgG anti-elastase as ligands, in association with Sephacryl gel filtration. The .alpha.1.AP-HPE11 complex was shown to bind with aorta and with purified aortic elastin. In both cases, the complex exhibited elastinolytic activity.This publication has 24 references indexed in Scilit:
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