A Study of the Interaction of Alleles at the Eyeless Locus

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Abstract
Three recessives and 2 dominant alleles at the eyeless locus in Drosophila melanogaster were crossed in isogenic stocks so as to obtain all possible combinations. The eye sizes of the various genotypes were classified. The results indicate that the dominant allele, ey D39k, is hypomorphic since when homozygous or in combination with a recessive allele the eye is larger than that of ey D39k / + . A type of double action is suggested[long dash]one to cancel or modify the action of the wild-type and 2d to act constructively. Eyeless-D, however, is not a hypomorph, but limits the size of the eye.

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