Preimplantation genetic testing for Huntington disease and certain other dominantly inherited disorders

1 February 1996

journal article
Published by Wiley in Clinical Genetics

Vol. 49 (2) , 57-58
https://doi.org/10.1111/j.1399-0004.1996.tb04327.x

Abstract

Preimplantation genetic testing (PGT) on embryos from couples at risk for Huntington disease can achieve disease prevention in offspring without disclosure of parental genotype. This strategy may also be applicable to other extremely deleterious dominant traits.

Keywords

ANTENATAL DIAGNOSIS
DOMINANT TRAITS
HUNTINGTON DISEASE
IN VITRO FERTILIZATION (IVF)
PREIMPLANTATION GENETIC TESTING
PREVENTION

This publication has 4 references indexed in Scilit:

Preimplantation genetic diagnosis
Current Opinion in Pediatrics, 1994
The current status of preimplantation diagnosis
Current Obstetrics & Gynaecology, 1994
Reluctance to undergo predictive testing: The case of Huntington Disease
American Journal of Medical Genetics, 1993
UPTAKE OF PRESYMPTOMATIC PREDICTIVE TESTING FOR HUNTINGTON'S DISEASE
The Lancet, 1989