CEREBRAL GRANULAR-CELL TUMOR (MYOBLASTOMA) IN A DOG - CASE-REPORT AND LITERATURE-REVIEW

  • 1 January 1978
    • journal article
    • review article
    • Vol. 68  (4) , 506-520
Abstract
An infiltrative granular cell tumor (myoblastoma) occurred in the superficial parietooccipital cortex of an ataxic 12-yr-old dog. The neoplasm was characterized by cells with numerous small PAS[periodic acid Schiff]-positive, diastase-resistant cytoplasmic granules. The neoplasm also had numerous cells with large globular PAS-positive bodies (angulate bodies). Ultrastructurally, the neoplastic cells were characterized by numerous homogeneous electron-dense, sharply bounded granules and large, pleomorphic, indistinctly bounded granules. The angulate bodies were composed of 8- to 10-nm fibrils, a few of which formed parallel arrays or tubule-like structures. This represents the 1st report of a granular cell tumor in the CNS of the dog.

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