Synthesis of the E‐ and Z‐isomers of the potent mutagen (S)‐fecapentaene‐12 by the Horner‐Wittig reaction
- 1 January 1985
- journal article
- research article
- Published by Wiley in Recueil des Travaux Chimiques des Pays-Bas
- Vol. 104 (11) , 307-308
- https://doi.org/10.1002/recl.19851041109
Abstract
A synthesis of the E‐ and Z‐isomers of optically pure (S)‐fecapentaene‐12 is described. The method is based on the chromatographic separation of diastereomeric adducts, formed as intermediates in the Horner‐Wittig reaction of an all‐trans undecatetraenal with a chiral phosphine oxide.Keywords
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