Enzymatic Modification of Amylase Inhibitor Produced byStreptomycessp. No. 280
- 1 November 1979
- journal article
- research article
- Published by Oxford University Press (OUP) in Agricultural and Biological Chemistry
- Vol. 43 (11) , 2265-2272
- https://doi.org/10.1080/00021369.1979.10863809
Abstract
At least 4 kind s of amylase inhibitors are found in culture of Streptomyes sp. No. 280. A large amount of amylase inhibitors were produced by Streptomyces sp. No. 280 when cultivated on 3% oatmeal medium and MW of the inhibitors were transformed to smaller molecules during the cultivation time. The transformation of the amylase inhibitor resulted from degradation of its carbohydrate moiety by .alpha.-amylase in the culture broth. The amylase inhibitor was hydrolyzed partially by the action of taka-amylase A or hog pancreatic .alpha.-amylase. With hydrolyzation of amylase inhibitor by .alpha.-amylase, neutral sugar (mainly maltose) were liberated from the amylase inhibitor and a modified inhibitor was newly formed, but anylase inhibitory activity glucoamylase was not changed. The inhibitory activity against [rabbit] muscle phosphorylase was almost completely lost.This publication has 5 references indexed in Scilit:
- API-2c, a New Alkaline Protease Inhibitor Produced by Streptomyces griseoincarnatus Strain No. KTo-250Agricultural and Biological Chemistry, 1978
- API-2b, a New Alkaline Protease Inhibitor Produced byStreptomyces griseoincarnatusStrain No. KTo-250Agricultural and Biological Chemistry, 1978
- Purification and Some Properties of Amylase Inhibitor (S-AI)Agricultural and Biological Chemistry, 1977
- Further Purification of Amylase Inhibitor Produced byStreptomycessp.Agricultural and Biological Chemistry, 1976
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951