WOUND-HEALING IN CULTURED CORNEAL ENDOTHELIAL-CELLS

  • 1 January 1980
    • journal article
    • research article
    • Vol. 19  (7) , 793-801
Abstract
Following the application of needle, intraocular lens, freeze and laser wounds to the center of discrete 1 cm2 areas, density-limited monolayers of cultured rabbit corneal endothelium demonstrate wound healing responses similar to those in vivo corneas. The wounded monolayer reforms in a period consistent with in vivo and in vitro organ culture models. Cell motility characterstics apparently are not dependent upon an underlying Descemet''s membrane. Density-limited, cultured monolayers of corneal endothelial cells present a good model for studying the response of the endothelium to a variety of stimuli.

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