What can be concluded from the Oxcheck and British family heart studies: commentary on cost effectiveness analyses

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Abstract
Key messages A more meaningful measure, cost per life year gained, requires modelling of the longer term effect of that risk reductionIn terms of life years gained, the more intensive British family heart study intervention was more effective but less cost effective than the Oxcheck interventionThe cost effectiveness of these relative to other interventions crucially depends on the assumed duration of the risk reduction, which must persist for at least five years for either programme to be viewed as cost effectiveLarger trials with longer follow up would be required to fully assess the long term effectiveness and overall cost effectiveness of population cardiovascular screening Key messages A more meaningful measure, cost per life year gained, requires modelling of the longer term effect of that risk reductionIn terms of life years gained, the more intensive British family heart study intervention was more effective but less cost effective than the Oxcheck interventionThe cost effectiveness of these relative to other interventions crucially depends on the assumed duration of the risk reduction, which must persist for at least five years for either programme to be viewed as cost effectiveLarger trials with longer follow up would be required to fully assess the long term effectiveness and overall cost effectiveness of population cardiovascular screening