Biosynthesis of dictamnine. The origin of the quinoline nucleus

Abstract
The biosynthesis of dictamnine, a furoquinoline alkaloid, was studied in intact Dictamnus albus plants. The quinoline ring system is derived from anthranilic acid and acetate. Tryptophan is not a precursor. Anthranilic acid concentration appears to control the rate of dictamnine biosynthesis in intact D. albus.