Early events and mechanisms in the induction of bacterial SOS functions: analysis of the phage repressor inactivation process in vivo.
- 1 April 1978
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 75 (4) , 1657-1661
- https://doi.org/10.1073/pnas.75.4.1657
Abstract
Different inducing agents and treatments produced distinctly different kinetic patterns of inactivation of prophage [.vphi.80] repressor molecules. The different patterns were related to differences in the initial altered states of DNA that were produced. The timing of appearance of DNA degradation was correlated with the time needed for repressor inactivation. These characteristics suggest that all the inducing treatments lead to the formation of a final predegradative DNA structure(s) (probably involving scissions) that is acted on by specific DNases, including the recBC DNase, to produce the signals for the induction of prophage.This publication has 27 references indexed in Scilit:
- Identification of the recA ( tif ) gene product of Escherichia coliProceedings of the National Academy of Sciences, 1977
- Protein X is the product of the recA gene of Escherichia coli.Proceedings of the National Academy of Sciences, 1977
- Inactivation and proteolytic cleavage of phage lambda repressor in vitro in an ATP-dependent reaction.Proceedings of the National Academy of Sciences, 1977
- A protease inhibitor blocks SOS functions in Escherichia coli: antipain prevents lambda repressor inactivation, ultraviolet mutagenesis, and filamentous growth.Proceedings of the National Academy of Sciences, 1977
- Identification of protein X of Escherichia coli as the recA + /tif + gene productMolecular Genetics and Genomics, 1977
- Colicin E2 is DNA endonuclease.Proceedings of the National Academy of Sciences, 1976
- Phleomycin-induced lethality and DNA degradation in Escherichia coli K12Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1975
- Model for regulation of Escherichia coli DNA repair functions.Proceedings of the National Academy of Sciences, 1975
- A MOLECULAR MECHANISM OF MITOMYCIN ACTION: LINKING OF COMPLEMENTARY DNA STRANDSProceedings of the National Academy of Sciences, 1963
- Isolation and identification of the irradiation product of thymineBiochimica et Biophysica Acta, 1960