Clonal identification of Burkitt's Lymphoma Arising from Lymphocyte‐Predominant Hodgkin's Disease
- 1 November 1996
- journal article
- case report
- Published by Wiley in British Journal of Haematology
- Vol. 95 (2) , 380-382
- https://doi.org/10.1046/j.1365-2141.1996.d01-1914.x
Abstract
The occurrence of large cell lymphomas subsequent to, or concurrent with, lymphocyte predominant Hodgkin's disease (LPHD) is a well‐documented phenomenon. We present a case of Burkitt's lymphoma of the bladder, occurring after the successful treatment of LPHD of a cervical lymph node. To evaluate the clonal relationship of the two tumours, we amplified the complementarity‐determining‐region 3 of two samples from paraffin‐embedded slides, using the polymerase chain reaction (PCR). The sequences of the PCR products showed 96% homology to each other. These results indicate that the malignant clone of Burkitt's lymphoma arose from the corresponding LPHD.Keywords
This publication has 0 references indexed in Scilit: