Immunocytological detection and localization of a peptide reacting with an ?-endorphin antiserum in the corticotropic and melanotropic cells of the trout pituitary (Salmo irideus Gibb)

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Abstract
Summary In the pituitary of the trout, the corticotropic and melanotropic cells display a strong immunocytological reaction with α-endorphin antiserum. This reaction persists even when a-endorphin antisera treated with β-1-24 ACTH or α-MSH are used. In the absence of pharmacological tests on the endorphic potencies of the compounds involved in the immunoreaction, it is not yet clear whether this reaction is due to the presence of an α-endorphin-like peptide or simply an immunologically related peptide without the properties of endorphin. However, the presence of such peptides in the fish pituitary is interesting from the comparative point of view.