Karyotype distributions in a stochastic model of reciprocal translocation.
Open Access
- 1 January 1996
- journal article
- Published by Cold Spring Harbor Laboratory in Genome Research
- Vol. 6 (1) , 1-9
- https://doi.org/10.1101/gr.6.1.1
Abstract
A random process of reciprocal translocation for a fixed number k of chromosomes (or arms) will have an equilibrium distribution of chromosome lengths. In this paper we calculate this distribution, by analytical means for k = 2 and partially for k = 3, and simulate the means of the marginal distributions for higher k. We compare this with a random (i.e., ahistorical) distribution of genomic DNA among k chromosomes and to a selection of karyotypes of real organisms. The results motivate a revised model where translocations giving rise to undersize chromosomes are disadvantaged.Keywords
This publication has 12 references indexed in Scilit:
- Exact and approximation algorithms for sorting by reversals, with application to genome rearrangementAlgorithmica, 1995
- Transforming cabbage into turnipPublished by Association for Computing Machinery (ACM) ,1995
- Polynomial-time algorithm for computing translocation distance between genomesPublished by Springer Nature ,1995
- Efficient bounds for oriented chromosome inversion distancePublished by Springer Nature ,1994
- Analytical approaches to genomic evolutionBiochimie, 1993
- MODELS AND ANALYSES OF GENOMIC EVOLUTIONPublished by World Scientific Pub Co Pte Ltd ,1993
- Gene order comparisons for phylogenetic inference: evolution of the mitochondrial genome.Proceedings of the National Academy of Sciences, 1992
- Edit distance for genome comparison based on non-local operationsPublished by Springer Nature ,1992
- Lengths of chromosomal segments conserved since divergence of man and mouse.Proceedings of the National Academy of Sciences, 1984
- Chemoprophylaxis with Diazouracil of Poliomyelitis in MiceScience, 1957