PATHOLOGY OF THE PLACENTA AND NEWBORN PUPS WITH SUSPECTED INTRA-UTERINE INFECTION OF CANINE HERPESVIRUS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 40  (9) , 1236-1240
Abstract
Pathologic and virologic investigations were done on the fetal placenta and on pup runts obtained from a bitch with a medical history of canine herpesvirus (CHV) infection. Macroscopically, the placenta was poorly developed. Small grayish white foci were observed in the placental labyrinth. Characteristic CHV infection lesions were not prominent in pups examined. Microscopically, focal degenerative and necrotizing lesions were observed in the placental labyrinth. Rarely, eosinophilic or basophilic intranuclear inclusion bodies were in the trophoblastic cells of the necrotizing lesions. In the adrenal gland of one stillborn pup, focal necrosis and hemorrhages could be seen; these irregularities were essentially the same as those seen in newborn pups with CHV infection. Focal interstitial pneumonia was observed in some pups. The CHV organism was isolated from the kidney of 1 pup that survived for 22 days.