Horizontal gene transfer in eukaryotic evolution
Top Cited Papers
- 1 August 2008
- journal article
- review article
- Published by Springer Nature in Nature Reviews Genetics
- Vol. 9 (8) , 605-618
- https://doi.org/10.1038/nrg2386
Abstract
Horizontal gene transfer (HGT; also known as lateral gene transfer) has had an important role in eukaryotic genome evolution, but its importance is often overshadowed by the greater prevalence and our more advanced understanding of gene transfer in prokaryotes. Recurrent endosymbioses and the generally poor sampling of most nuclear genes from diverse lineages have also complicated the search for transferred genes. Nevertheless, the number of well-supported cases of transfer from both prokaryotes and eukaryotes, many with significant functional implications, is now expanding rapidly. Major recent trends include the important role of HGT in adaptation to certain specialized niches and the highly variable impact of HGT in different lineages.Keywords
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