Coenzyme Q Metabolism in Pantothenic Acid Deficiency.

1 August 1961

journal article
research article
Published by Frontiers Media SA in Experimental Biology and Medicine

Vol. 107 (4) , 911-914
https://doi.org/10.3181/00379727-107-26792

Abstract

Pantothenic acid (PA) deficiency in rats results in decreases in coenzyme Q (CoQ) and succinoxidase activity of liver. Administration of PA to deficient rats restores these enzymes to normal in 24 hours. Deficient animals show decreased incorporation of labeled acetate and mevalonate into liver CoQ, indicating a decreased synthesis of CoQ in PA deficiency.

Keywords

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