Coupling ratio of electrogenic Na+-alanine cotransport in isolated rat hepatocytes
- 15 February 1983
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 210 (2) , 621-624
- https://doi.org/10.1042/bj2100621
Abstract
Na+-alanine cotransport across the cell membrane in isolated rat hepatocytes was studied. Changes in the cell membrane potential associated with the transport of alanine interfere with determination of the Na+-alanine coupling ratio of the cotransport. With valinomycin present to ‘clamp’ the cell membrane potential, a coupling ratio of 1:1 for the Na+-alanine influx was obtained.This publication has 12 references indexed in Scilit:
- Energization of alanine transport in isolated rat hepatocytes. Electrogenic Na+-alanine co-transport leading to increased K+ permeability.Journal of Biological Chemistry, 1980
- The mechanism of Na+-dependent D-glucose transport.Journal of Biological Chemistry, 1980
- Evidence for an intestinal Na+: Sugar transport coupling stoichiometry of 2.0Biochimica et Biophysica Acta (BBA) - Biomembranes, 1980
- Equilibrium and steady-state models of the coupling between the amino acid gradient and the sodium electrochemical gradient in mouse ascites- tumour cellsBiochemical Journal, 1978
- Exchange of 3-O-methylglucose in isolated fat cells. Concentration dependence and effect of insulin.Journal of Biological Chemistry, 1976
- Substrate-induced membrane potential changes in the perfused rat liverBiochimica et Biophysica Acta (BBA) - Biomembranes, 1974
- Sodium and Sugar Fluxes across the Mucosal Border of Rabbit IleumThe Journal of general physiology, 1969
- A net gain of sodium ions and a net loss of potassium ions accompanying the uptake of glycine by mouse ascites-tumour cells in the presence of sodium cyanideBiochemical Journal, 1968
- Change in Na+ uptake during amino acid transportBiochimica et Biophysica Acta (BBA) - Biomembranes, 1967
- Kinetic Relations of the Na-Amino Acid Interaction at the Mucosal Border of IntestineThe Journal of general physiology, 1967