A Simple Method for Introducing -SH/COOH Group at 5?-OH end of Oligonucleotide
- 1 June 1992
- journal article
- research article
- Published by Taylor & Francis in Nucleosides and Nucleotides
- Vol. 11 (5) , 999-1002
- https://doi.org/10.1080/07328319208021163
Abstract
A method for introducing a -SH group at the 5′-end of the oligonucleotide using S-Trityl-L-Cysteine has been developed. Carbonyl diimidazole was used for activating the 5′-OH group.Keywords
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