Detection of cancer cells disseminated in bone marrow using real-time quantitative RT-PCR of CEA, CK19, and CK20 mRNA in patients with gastric cancer
Open Access
- 24 November 2006
- journal article
- Published by Springer Nature in Gastric Cancer
- Vol. 9 (4) , 308-314
- https://doi.org/10.1007/s10120-006-0398-z
Abstract
To determine the significance of bone marrow disseminated tumor cells in gastric cancer, we investigated the mRNA expression levels of carcinoembryonic antigen (CEA), cytokeratin 19 (CK19), and cytokeratin 20 (CK20) using the real-time quantitative reverse-transcription polymerase chain reaction (RQ-PCR).Keywords
This publication has 26 references indexed in Scilit:
- A Pooled Analysis of Bone Marrow Micrometastasis in Breast CancerNew England Journal of Medicine, 2005
- Prognostic significance of peritoneal minimal residual disease in gastric cancer detected by reverse transcription–polymerase chain reactionBritish Journal of Surgery, 2004
- Bone marrow micrometastases predict early post-operative recurrence following surgical resection of oesophageal and gastric carcinomaEuropean Journal of Surgical Oncology, 2003
- Bone marrow micrometastasis in breast cancerBritish Journal of Surgery, 2003
- Minimal Residual Disease in Gastric CancerPublished by Springer Nature ,2003
- Detection and clinical significance of occult tumour cells in colorectal cancerBritish Journal of Surgery, 2001
- Japanese Classification of Gastric Carcinoma – 2nd English Edition –Gastric Cancer, 1998
- Frequency and prognostic significance of isolated tumour cells in bone marrow of patients with non-small-cell lung cancer without overt metastasesThe Lancet, 1996
- Prognostic significance of micrometastatic tumour cells in bone marrow of colorectal cancer patientsThe Lancet, 1992
- Micrometastatic tumour cells in bone marrow of patients with gastric cancer: Methodological aspects of detection and prognostic significanceEuropean Journal of Cancer and Clinical Oncology, 1991