ROLE OF THE NERVOUS SYSTEM IN EXPERIMENTAL RENAL HYPERTENSION

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Abstract
286 expts. were performed on 65 trained dogs. Some of these animals were normotensive, most had renal hypertension for a short or prolonged period of time, and 2 were neurogenic hypertensives. The anesthetic agents; ether, thiopental, pentobar-bital sodium, and morphine and the "adrenergic blocking agents;" TEAC, dibenamine, 883F and D.H.E. 45 were used. Tests were also made using procaine (epidural), hypercapnic stimulation and a cold pressor test. It is concluded that the nervous system plays no more important role in maintaining the blood pressure level of renal hypertensive dogs than it plays in maintaining the blood pressure level of normal dogs.