A Clinicopathological Study of 13 Danish Cases of Burkitt's Lymphoma

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Abstract
During a 4‐year period 24 cases of malignant non‐Hodgkin's lymphomas were proposed to be of the Burkitt‐type (BL) by at least 1 of 5 pathologists of the Lymphoma Registry in Jutland, Denmark. When the histological material was critically reviewed the diagnosis could be maintained in only 13 cases. 9 of the remaining 11 cases were immunoblastic lymphomas (IBL). Immunohistochemical stainings for cytoplasmic Ig‐chains revealed generally weak reactions in the cases of BL. A distinct B‐zone homing phenomenon first appearing in the lymphocytic mantle zone was observed in several lymph nodes from 2 patients with BL. In the BL‐group the correlation between initial clinical stage and survival was satisfactory, the 2‐year survival rate being 38 % in the total BL‐group. The incidence of BL was 2.1 % of the malignant non‐Hodgkin's lymphomas in the registry.