New developments in the multi-site phosphorylation and integration of stress signalling at p53
- 1 January 1998
- journal article
- review article
- Published by Taylor & Francis in International Journal of Radiation Biology
- Vol. 74 (6) , 729-737
- https://doi.org/10.1080/095530098141005
Abstract
To summarize recent progress in the understanding of the role of multi-site phosphorylation in mediating the integration of stress signals at the p53 tumour suppressor protein.Keywords
This publication has 44 references indexed in Scilit:
- Synergy between the Mos/Mitogen-Activated Protein Kinase Pathway and Loss of p53 Function in Transformation and Chromosome InstabilityMolecular and Cellular Biology, 1997
- p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells.Genes & Development, 1996
- EDITORIAL. p53—INTEGRATING THE COMPLEXITYThe Journal of Pathology, 1996
- Phosphorylation of p53 at the casein kinase II site selectively regulates p53-dependent transcriptional repression but not transactivationNucleic Acids Research, 1996
- p53 in signaling checkpoint arrest or apoptosisCurrent Opinion in Genetics & Development, 1996
- p53 controls both the G2/M and the G1 cell cycle checkpoints and mediates reversible growth arrest in human fibroblasts.Proceedings of the National Academy of Sciences, 1995
- A p53-Dependent Mouse Spindle CheckpointScience, 1995
- Transcriptional activation by p53 correlates with suppression of growth but not transformationCell, 1994
- p53-Dependent apoptosis in the absence of transcriptional activation of p53-target genesNature, 1994
- WAF1, a potential mediator of p53 tumor suppressionCell, 1993