Hepatitis B Vaccination and Hepatocellular Carcinoma Rates in Boys and Girls
Open Access
- 20 December 2000
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 284 (23) , 3040-3042
- https://doi.org/10.1001/jama.284.23.3040
Abstract
Hepatocellular carcinoma (HCC) occurs mainly in adults 40 to 60 years of age.1 However, in areas hyperendemic for hepatitis B virus (HBV) infection, HCC may develop in children.2 We have found a nearly 100% hepatitis B surface antigen seropositivity rate in Taiwanese children with HCC, indicating an intimate relationship between HBV and childhood HCC.2 In 1984, a hepatitis B vaccination program was launched and has effectively reduced the prevalence of HBV infection, chronic HBV infection rate,3 and incidence of HCC in children in Taiwan.4Keywords
This publication has 1 reference indexed in Scilit:
- A mass vaccination program in Taiwan against hepatitis B. virus infection in infants of hepatitis B surface antigen-carrier mothersInternational Journal of Gynecology & Obstetrics, 1988