The Association of Histocompatibility Antigens of the B7 Cross-Reacting Group with Peyronie’s Disease

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Abstract
A significant relationship between [human] Peyronie''s disease and histocompatibility antigens of the B7 cross-reacting group is described. The association of Peyronie''s disease with a group of immunologically cross-reacting antigens, rather than with a single antigen, suggests that a yet undetermined agent of specific molecular configuration involves in some way its pathogenesis. This finding has diagnostic application and adds a new dimension to the etiologic investigation of Peyronie''s disease.