Dialytic Therapy for Irreversible Uremia

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Abstract
(Second of Two Parts)Modifications of Hemodialysis TherapySequential Ultrafiltration and DialysisPatients on MH rely mainly on ultrafiltration to remove salt and water that accumulate despite insensible losses and residual urine output. During hemodialysis, a hydrostatic pressure gradient is created across the dialysis membrane so that fluid and solutes leave the blood and enter the dialysate. Ultrafiltrative extraction of 1 to 2 liters in four to six hours usually entails no difficulty. Removing large volumes of fluid (over 3 liters) from patients who gain excessive weight between dialyses may be poorly tolerated and is frequently associated with hypotension or . . .

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