THIOGLYCOLIC ACID POISONING IN CONNECTION WITH THE "COLD WAVE" PROCESS

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Abstract
For some time thioglycolic acid has been used in industry as an iron indicator with no reported ill effects on the handlers. A few years ago a process of hair curling was put on the market known as the "Cold Wave," in which this chemical is employed. There are variations in the basic solutions as put out by different manufacturers, but thioglycolic acid in dilutions up to 5 per cent is a constituent of all those investigated. By the technic employed, the horny sheath of the hair fiber is softened while it is rolled round a spindle, following which it hardens into a permanent spiral. The sulfur and aminocarboxyl compounds in the keratin scales are disrupted by the thioglycolic acid, HSCH2COOH, which is applied with an excess of ammonia. After varying periods the acid is washed off with water or hydrogen peroxide. The cases in which a toxic reaction has

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