Prenatal diagnosis of del(15)(q11q13)
- 1 June 1990
- journal article
- research article
- Published by Wiley in Prenatal Diagnosis
- Vol. 10 (6) , 405-411
- https://doi.org/10.1002/pd.1970100608
Abstract
A case of del(15)(q11q13) was detected in amniotic fluid cell cultures and confirmed by cordocentesis in a 27‐year‐old woman with a low maternal serum alpha‐fetoprotein level. The fetus was shown to have a short femoral length on ultrasonography. This structural chromosome abnormality associated with the prenatal ultrasonographic findings and the morphological characteristics visualized after termination of pregnancy strongly suggest Prader‐Willi syndrome.Keywords
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