A Convenient Synthesis of Two New Indoloquinoline Alkaloids

Abstract
A concise synthesis of two new indoloquinoline-based alkaloids (1 and 2), isolated from Cryptolepis sanguinolenta, is reported. The palladium-catalyzed cross-coupling reaction of 3-bromoquinoline derivatives with N-pivaloylamine phenylboronic acid gave the corresponding biaryls from which the indoloquinoles could be synthesized.

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