Synthesis of optically active prenylamine from (-)-norephedrine.
- 1 January 1976
- journal article
- research article
- Published by Pharmaceutical Society of Japan in CHEMICAL & PHARMACEUTICAL BULLETIN
- Vol. 24 (5) , 1033-1039
- https://doi.org/10.1248/cpb.24.1033
Abstract
Optically active prenylamine [a cardiovascular drug] was synthesized from natural (-)-norephedrine, through the aziridine derivatives. The absolute configuration of (+)-prenylamine was confirmed to have (S)-configuration by the synthesis. Further, the pharmacological activity was examined.This publication has 0 references indexed in Scilit: